May 12, 2011 Evidence for Human Lung Stem Cells


Human lungs contain undifferentiated human lung stem cells nested in niches in the distal airways. These cells are self-renewing, clonogenic, and multipotent in vitro. After injection into damaged mouse lung in vivo, human lung stem cells form human bronchioles, alveoli, and pulmonary vessels integrated structurally and functionally with the damaged organ. The formation of a chimeric lung was confirmed by detection of human transcripts for epithelial and vascular genes. In addition, the self-renewal and long-term proliferation of human lung stem cells was shown in serial-transplantation assays.

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2 Responses to May 12, 2011 Evidence for Human Lung Stem Cells

  1. Administrator says:

    I’m not that technical but normally I would say.. Yes

  2. Elza says:

    Your blog is very simple but I like it because it is very well structured.

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