Tag Archives: Nintedanib

December 01 2013 – Human stem cells converted to functional lung cells

NEW YORK, NY — For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells. The advance, reported by Columbia University Medical Center (CUMC) researchers, has significant potential for modeling lung disease, screening … Continue reading

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November 27 2013 – FibroGen Announces Observations of Possible Disease Stabilization and Improvement in Interim Analysis of Phase 2 Study of FG-3019

SAN FRANCISCO–(BUSINESS WIRE)–FibroGen, Inc. (FibroGen), announced today that interim results from an ongoing open-label Phase 2 clinical study to evaluate FG-3019 as a treatment for idiopathic pulmonary fibrosis (IPF) continue to suggest that the investigational drug has the potential to … Continue reading

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November 15 2013 – Enzo Biochem Announces Study in Leading Scientific Journal Linking Idiopathic Pulmonary Fibrosis, a Deadly Human Disease with No Effective Treatment Options, to Presence of a Monkey Virus

Enzo Biochem Inc. (NYSE:ENZ) today announced publication of a study in a leading scientific journal Modern Pathology a Nature Publishing Group publication that shows a strong association of idiopathic pulmonary fibrosis (IPF) a pulmonary disease with 100% mortality within five … Continue reading

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November 10 2013 – Research by Saint Louis University scientists offers way to disrupt fibrosis

ST. LOUIS – A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis – a condition where the body’s natural process of forming scars … Continue reading

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November 4 2013 – Development Plan for PTL-202, a Treatment for Progressive Organ Scarring, a $1.1 Billion Opportunity

Worldwide, there are over 5,000,000 people living with Idiopathic Pulmonary Fibrosis (IPF)(IPF Coalition).IPF therapy sales across the US, France, Germany, Italy, Spain, and the UK to rise to over $1.1 billion by 2017, at a Compound Annual Growth Rate (CAGR) … Continue reading

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October 28 2013 – Ambrisentan (Letairis) stopped early in IPF trial (Annals Int Med)

Ambrisentan (Letairis) stopped early in IPF trial A large phase III randomized trial testing Ambrisentan (Letairis) for early idiopathic pulmonary fibrosis was stopped early after an interim analysis of the data showed possible harm. The results were reported in Annals of … Continue reading

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October 21 2013 – Chronic hypersensitivity pneumonitis in patients diagnosed with idiopathic pulmonary fibrosis: a prospective case-cohort study

Chronic hypersensitivity pneumonitis in patients diagnosed with idiopathic pulmonary fibrosis: a prospective case-cohort study Original Text Prof Ferran Morell MD a b , Ana Villar MD a b, María-Ángeles Montero MD c d †, Xavier Muñoz MD a b, Prof … Continue reading

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October 18 2013 – UW researchers to test novel therapy for idiopathic pulmonary fibrosis

Dear Colleagues: I am very pleased to report that UW researchers have received a grant from the National Institutes of Health (NIH) to test a promising, novel surgical therapy for treating idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive … Continue reading

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October 13 2013 – Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice

Despite the established role of alveolar type II epithelial cells for the maintenance of pulmonary function, little is known about the deregulation of lipid composition in the pathogenesis of pulmonary fibrosis. The elongation of long-chain fatty acids family member 6 … Continue reading

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October 11 2013 – UAB gets $9.7 million to find treatments for deadly lung disease pulmonary fibrosis

UAB gets $9.7 million to find treatments for deadly lung disease pulmonary fibrosis by Bob Shepard Grant will allow UAB researchers to study novel therapies for pulmonary fibrosis, a deadly lung disease with no approved treatments. The University of Alabama at … Continue reading

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