August 5 2013 – Oral N-acetylcysteine (NAC) reduces COPD exacerbations in RCT (Chest)

Oxidative stress (imbalance between oxidants and antioxidants) is part of the story of how COPD causes symptoms of cough and shortness of breath. Cigarette smoke is the main source of oxidation damage in the lungs leading to COPD, but even after they quit smoking, people with COPD still have a so-called “redox imbalance” that contributes to their daily COPD symptoms.

N-acetylcysteine (NAC) is an antioxidant, anti-inflammatory, anti-mucus medicine that has already been tested in people with COPD as an oral drug. Also called Mucomyst, N-acetylcysteine was no blockbuster at preventing COPD exacerbations or improving symptoms — most trials did not show a benefit — but reviews and analyses have produced some optimism:

Read the entire article at:

http://pulmccm.org/2013/randomized-controlled-trials/n-acetylcysteine-reduces-copd-exacerbations-in-rct-chest/?art

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