June 27 2011 Duke researchers learn how lung fibrosis begins and could be treated

DURHAM, N.C. – An invasive cell that leads to fibrosis of the lungs may be stopped by cutting off its supply of sugar, according to researchers at Duke University Medical Center.

Idiopathic pulmonary fibrosis (IPF), which affects about 100,000 people in the U.S. each year and leads to death within three years of diagnosis, has only one therapy in the U. S.: lung transplantation.

Duke researchers have found a possible new treatment by identifying a cell surface receptor on the invasive cells called myofibroblasts and an enzyme that produces a sugar the receptor recognizes.

Read the entire article at:

http://www.eurekalert.org/pub_releases/2011-06/dumc-drl062311.php


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